STREAMING NOW: Watch Now

Study Looks at How Aspirin Interacts with Pain Relievers

New research shows adding aspirin to popular prescription arthritis drugs – celecoxib, known as celebrex, ibuprofen, or naproxen – slightly changes how they interact with the cardiovascular system, but for the most part they’re safe to take together.

Posted: Apr 17, 2018 7:34 AM

CLEVELAND – There’s reassuring information for more than 50 million Americans who suffer from arthritis pain.

New research shows adding aspirin to popular prescription arthritis drugs – celecoxib, known as celebrex, ibuprofen, or naproxen – slightly changes how they interact with the cardiovascular system, but for the most part they’re safe to take together.

“We found overall that you can take aspirin safely with these drugs,” said Steve Nissen, M.D., chairman of Cardiovascular Medicine at Cleveland Clinic and the study’s first author. “There are still advantages to taking celecoxib rather than ibuprofen, or naproxen, but if anything, the drugs are overall reasonable to take with aspirin.”

Researchers analyzed data from the 2016 ‘Precision’ trial where authors studied more than 24,000 people with osteoarthritis and rheumatoid arthritis who were at high risk for heart disease.

Participants took daily prescription doses of either ibuprofen, naproxen, or celecoxib.

The 2016 study showed the heart risk for the drugs was basically equivalent, and that celecoxib had the fewest gastrointestinal and kidney complications.

The new study looked at ‘Precision’ participants who were also taking aspirin and investigated how aspirin may change the safety of the three prescription pain relievers.

Results showed that taking aspirin with any of the three drugs is relatively safe, however the safety of celecoxib, compared to ibuprofen or naproxen, was narrowed a bit when taken with aspirin.

Nissen said the new information should not cause worry, but it is important for people who take prescription pain relievers and aspirin to talk to their doctor.

“I do think that patients that take these pain relievers, particularly in full therapeutic doses, will want to discuss with their doctor if they are also taking aspirin to make certain that they’re making the best possible choices,” said Dr. Nissen.

Article Comments

Medford
Clear
58° wxIcon
Hi: 95° Lo: 59°
Feels Like: 58°
Brookings
Clear
55° wxIcon
Hi: 73° Lo: 55°
Feels Like: 55°
Crater Lake
Clear
47° wxIcon
Hi: 85° Lo: 54°
Feels Like: 47°
Grants Pass
Clear
54° wxIcon
Hi: 91° Lo: 61°
Feels Like: 54°
Klamath Falls
Clear
47° wxIcon
Hi: 88° Lo: 50°
Feels Like: 47°
Dangerously Hot Next Week
KDRV Radar
KDRV Fire Danger
KDRV Weather Cam

Community Events

Latest Video

Image

Retired couple and divers recover drowning victim's body from Lost Creek Lake

Image

Curry County turns away from Tsunami sirens

Image

Take a Hike: Bandersnatch Trail

Image

A quite hero

Image

Highway 199 crashes

Image

Daily J! - Street Art

Image

Thursday, August 22 evening weather

Image

I the Kitchen: Italian Sausage Frittata

Image

Pet of the Week: Lona

Image

Thursday, August 22 afternoon weather