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Oregon gets shipments of experimental COVID-19 drug

The Oregon Health Authority says patients need to meet specific guidelines to take the drug.

Posted: May 17, 2020 10:31 AM

SALEM, Ore --- Oregon has received remdesivir. Providence St. Vincent and Providence Portland medical centers are doing their own clinical trials with the drug. The hospitals have tested 30 patients. 

“The Oregon Health Authority is committed to distributing Oregon’s allotment of remdesivir to Oregon hospitals for the treatment of patients with severe COVID-19 in accordance with the FDA’s Emergency Use Authorization,” said Dr. Dana Hargunani, Chief Medical Officer. “Because of the experimental nature of the drug, shared decision-making between patients and providers is paramount, and informed consent must be obtained prior to its use.”

Remdesivir is approved by the Food and Drug Administration (FDA). It is an experimental drug for patients hospitalized with severe COVID-19. The state received this drug on May 12th and May 15th. States are allowed to use this drug under a federally issued Emergency Use Authorization (EUA). 


BACKGROUND ON EUA FROM THE OREGON HEALTH AUTHORITY:  

The EUA allows health professionals to use the drug to treat some severely ill COVID-19 patients who meet clinical criteria. Remdesivir was developed by Gilead Sciences Inc. and has been tested in patients with various diseases, such as Ebola, Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). According to Gilead’s website, “it is not known if remdesivir is safe and effective for the treatment of COVID-19.”


The Oregon Health Authority says this drug has been tested on 1,063 patients. The National Institute for Allergy and Infectious Disease treated patients with the drug. These patients had a faster recovery. The results released in April show patients with advanced lung disease recovered 31 percent faster with the drug than patients who didn't take it. The study says differences in mortality rate were not statistically significant. The full results from the study have not been published. 

“Clinical observation by providers across the board has been that overall clinical improvement and in particular fever resolution, is sped up by the drug’s administration. It has varied by the stage of the patients’ degree of illness at time of presentation. Those findings were confirmed in the recent preliminary data release by Gilead last week – patients were able to discharge 4 to 5 days sooner with drug therapy.” said Dr. Tobias Pusch, an infectious disease physician at Providence.

The drug will be given to hospitals when a patient is eligible. There are specific guidelines that need to be met under the EUA. 

The Oregon Health Authority says, "as of May 16, at 8:30 a.m. there were 56 people hospitalized with confirmed COVID 19. Among those 25 are being treated in an intensive care unit." 

Learn more here: https://sharedsystems.dhsoha.state.or.us/DHSForms/Served/le2389D.pdf

Oregon Coronavirus Cases

Data is updated nightly.

Confirmed Cases: 9294

Reported Deaths: 209
CountyConfirmedDeaths
Multnomah230169
Marion156447
Washington144620
Clackamas77324
Umatilla6204
Union3471
Lincoln3272
Deschutes1920
Lane1803
Linn1549
Polk14912
Malheur1401
Jackson1310
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Jefferson1260
Klamath1231
Hood River880
Benton835
Wasco751
Morrow721
Clatsop490
Douglas440
Coos410
Josephine411
Columbia310
Lake190
Tillamook120
Crook110
Wallowa100
Curry70
Baker40
Grant10
Harney10
Sherman10
Gilliam00
Unassigned00
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Confirmed Cases: 246550

Reported Deaths: 6265
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Riverside18720465
San Diego15207377
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Imperial6824100
Alameda6384138
Fresno562677
Kern493977
Santa Clara4750159
Tulare4521133
San Joaquin429855
San Francisco371950
Sacramento355969
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Contra Costa332678
Santa Barbara326129
Ventura324047
Kings258332
Marin244619
Stanislaus239144
Monterey174815
Solano147625
Sonoma12299
Merced120811
Placer75411
San Luis Obispo6752
Yolo58324
Madera5665
Santa Cruz4103
Napa3444
San Benito2572
Lassen2340
Butte2063
El Dorado2060
Sutter2063
Humboldt1384
Shasta1354
Nevada1231
Glenn1220
Yuba1031
Tehama881
Lake850
Mendocino850
Colusa700
Calaveras530
Del Norte511
Tuolumne430
Mono411
Inyo321
Siskiyou310
Mariposa271
Amador260
Plumas110
Alpine20
Trinity20
Sierra10
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