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Oregon gets shipments of experimental COVID-19 drug

The Oregon Health Authority says patients need to meet specific guidelines to take the drug.

Posted: May 17, 2020 10:31 AM

SALEM, Ore --- Oregon has received remdesivir. Providence St. Vincent and Providence Portland medical centers are doing their own clinical trials with the drug. The hospitals have tested 30 patients. 

“The Oregon Health Authority is committed to distributing Oregon’s allotment of remdesivir to Oregon hospitals for the treatment of patients with severe COVID-19 in accordance with the FDA’s Emergency Use Authorization,” said Dr. Dana Hargunani, Chief Medical Officer. “Because of the experimental nature of the drug, shared decision-making between patients and providers is paramount, and informed consent must be obtained prior to its use.”

Remdesivir is approved by the Food and Drug Administration (FDA). It is an experimental drug for patients hospitalized with severe COVID-19. The state received this drug on May 12th and May 15th. States are allowed to use this drug under a federally issued Emergency Use Authorization (EUA). 


BACKGROUND ON EUA FROM THE OREGON HEALTH AUTHORITY:  

The EUA allows health professionals to use the drug to treat some severely ill COVID-19 patients who meet clinical criteria. Remdesivir was developed by Gilead Sciences Inc. and has been tested in patients with various diseases, such as Ebola, Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). According to Gilead’s website, “it is not known if remdesivir is safe and effective for the treatment of COVID-19.”


The Oregon Health Authority says this drug has been tested on 1,063 patients. The National Institute for Allergy and Infectious Disease treated patients with the drug. These patients had a faster recovery. The results released in April show patients with advanced lung disease recovered 31 percent faster with the drug than patients who didn't take it. The study says differences in mortality rate were not statistically significant. The full results from the study have not been published. 

“Clinical observation by providers across the board has been that overall clinical improvement and in particular fever resolution, is sped up by the drug’s administration. It has varied by the stage of the patients’ degree of illness at time of presentation. Those findings were confirmed in the recent preliminary data release by Gilead last week – patients were able to discharge 4 to 5 days sooner with drug therapy.” said Dr. Tobias Pusch, an infectious disease physician at Providence.

The drug will be given to hospitals when a patient is eligible. There are specific guidelines that need to be met under the EUA. 

The Oregon Health Authority says, "as of May 16, at 8:30 a.m. there were 56 people hospitalized with confirmed COVID 19. Among those 25 are being treated in an intensive care unit." 

Learn more here: https://sharedsystems.dhsoha.state.or.us/DHSForms/Served/le2389D.pdf

Oregon Coronavirus Cases

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Cases: 173626

Reported Deaths: 2457
CountyCasesDeaths
Multnomah34641566
Washington23309229
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Clackamas15216204
Lane11478144
Jackson9846127
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Deschutes698772
Linn410763
Yamhill407074
Malheur342558
Polk341752
Klamath340859
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Jefferson205932
Coos196631
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Morrow107815
Clatsop8838
Crook86819
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Curry5919
Tillamook5763
Lake4137
Grant4044
Harney3046
Wallowa1575
Sherman570
Gilliam551
Wheeler251
Unassigned00

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Reported Deaths: 60922
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Los Angeles122811823601
Riverside2972154525
San Bernardino2944644544
San Diego2745663662
Orange2687624886
Santa Clara1167722013
Kern1077641317
Sacramento1010581646
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Contra Costa66839781
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Tulare49383829
Monterey43260352
San Mateo41050560
San Francisco35947517
Santa Barbara33830446
Solano31875239
Merced31196452
Sonoma29632311
Imperial27920718
Kings22755245
Placer21751283
San Luis Obispo20917256
Madera16234239
Santa Cruz15554203
Marin13851226
Yolo13547199
Shasta11677217
Butte11529196
El Dorado9688109
Napa965479
Sutter9268109
Yuba609844
San Benito596963
Lassen566624
Tehama543056
Nevada444775
Tuolumne406664
Mendocino398747
Amador361646
Humboldt358737
Lake339943
Glenn235425
Colusa219216
Calaveras205551
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