Oregon gets shipments of experimental COVID-19 drug

The Oregon Health Authority says patients need to meet specific guidelines to take the drug.

Posted: May 17, 2020 10:31 AM

SALEM, Ore --- Oregon has received remdesivir. Providence St. Vincent and Providence Portland medical centers are doing their own clinical trials with the drug. The hospitals have tested 30 patients. 

“The Oregon Health Authority is committed to distributing Oregon’s allotment of remdesivir to Oregon hospitals for the treatment of patients with severe COVID-19 in accordance with the FDA’s Emergency Use Authorization,” said Dr. Dana Hargunani, Chief Medical Officer. “Because of the experimental nature of the drug, shared decision-making between patients and providers is paramount, and informed consent must be obtained prior to its use.”

Remdesivir is approved by the Food and Drug Administration (FDA). It is an experimental drug for patients hospitalized with severe COVID-19. The state received this drug on May 12th and May 15th. States are allowed to use this drug under a federally issued Emergency Use Authorization (EUA). 


BACKGROUND ON EUA FROM THE OREGON HEALTH AUTHORITY:  

The EUA allows health professionals to use the drug to treat some severely ill COVID-19 patients who meet clinical criteria. Remdesivir was developed by Gilead Sciences Inc. and has been tested in patients with various diseases, such as Ebola, Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). According to Gilead’s website, “it is not known if remdesivir is safe and effective for the treatment of COVID-19.”


The Oregon Health Authority says this drug has been tested on 1,063 patients. The National Institute for Allergy and Infectious Disease treated patients with the drug. These patients had a faster recovery. The results released in April show patients with advanced lung disease recovered 31 percent faster with the drug than patients who didn't take it. The study says differences in mortality rate were not statistically significant. The full results from the study have not been published. 

“Clinical observation by providers across the board has been that overall clinical improvement and in particular fever resolution, is sped up by the drug’s administration. It has varied by the stage of the patients’ degree of illness at time of presentation. Those findings were confirmed in the recent preliminary data release by Gilead last week – patients were able to discharge 4 to 5 days sooner with drug therapy.” said Dr. Tobias Pusch, an infectious disease physician at Providence.

The drug will be given to hospitals when a patient is eligible. There are specific guidelines that need to be met under the EUA. 

The Oregon Health Authority says, "as of May 16, at 8:30 a.m. there were 56 people hospitalized with confirmed COVID 19. Among those 25 are being treated in an intensive care unit." 

Learn more here: https://sharedsystems.dhsoha.state.or.us/DHSForms/Served/le2389D.pdf

Oregon Coronavirus Cases

Data is updated nightly.

Cases: 394569

Reported Deaths: 5243
CountyCasesDeaths
Multnomah60720847
Washington42359405
Marion40153516
Clackamas33040387
Lane30428361
Jackson25105363
Deschutes23795189
Umatilla15144184
Linn14859183
Douglas13523293
Josephine10278247
Yamhill9840143
Klamath9112149
Polk8325102
Benton615338
Malheur593292
Coos5768109
Columbia438056
Jefferson424366
Lincoln365852
Crook343057
Union340756
Wasco318646
Clatsop263635
Baker221833
Tillamook218046
Hood River216537
Morrow197825
Curry193939
Harney121333
Grant109116
Lake105617
Wallowa76313
Sherman1933
Gilliam1854
Wheeler1141
Unassigned00

California Coronavirus Cases

Data is updated nightly.

Cases: 5109348

Reported Deaths: 74802
CountyCasesDeaths
Los Angeles153635127246
San Diego4091824350
Riverside3892365381
San Bernardino3762805983
Orange3352965756
Sacramento1690952452
Kern1582701828
Fresno1574692270
Santa Clara1528571928
Alameda1256281512
San Joaquin1080791835
Ventura1043091192
Contra Costa1042181056
Stanislaus919641429
Tulare867391100
San Francisco57141674
San Mateo56585631
Monterey52842626
Solano47828360
Santa Barbara47523555
Merced45309671
Sonoma43349414
Placer42458473
Imperial38932776
Kings35370367
San Luis Obispo31667360
Madera26388311
Shasta26221461
Butte25608318
Santa Cruz22402224
Yolo21722261
Marin18587249
El Dorado18448168
Sutter14646186
Napa13446106
Yuba1079891
Tehama10316131
Humboldt10294119
Nevada10112105
Mendocino864999
Lassen797656
San Benito787979
Tuolumne778491
Lake7057113
Amador580067
Siskiyou479657
Glenn458536
Calaveras445788
Del Norte377942
Colusa328321
Inyo257346
Plumas19577
Mono19034
Mariposa162218
Trinity100717
Modoc7936
Sierra2190
Unassigned1560
Alpine1080
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