SEVERE WX : Red Flag Warning View Alerts
STREAMING NOW: Watch Now

A diabetes drug has been recalled because it contains high levels of cancer-causing agent

A widely-used diabetes drug has been recalled after manufa...

Posted: Oct 9, 2020 11:45 AM

A widely-used diabetes drug has been recalled after manufacturers found it contained unacceptably high levels of a cancer-causing contaminant.

Indian pharmaceutical company Marksans Pharma Limited is recalling metformin hydrochloride extended-release tablets because their levels of NDMA, a "probable human carcinogen," were higher than the acceptable daily intake limit of 96 nanograms per day, according to a recall published this week by the US Food and Drug Administration (FDA).

Metformin tablets are used to treat type 2 diabetes and are designed to lower glucose levels.

The recall applies to metformin tablets between 500 mg and 750 mg, sold under the brand name Time-Cap Labs, Inc.

The recall expands an earlier recall of the same product from this summer. But it's just one of several metformin products that have been found to contain NDMA in the last year. Seven other pharmaceutical companies have issued recalls for metformin hydrochloride extended-release tablets due to their carcinogenic contents.

The FDA is still investigating where NDMA comes from and how it ends up in metformin products. Most levels found in medications are generally low and fall within the FDA's accepted daily intake, but recently recalled medications exceed that. Marksans Pharma Limited, India, however, did not reveal how much NDMA its recalled products contained.

The recall applies to the following products, which can be identified by their National Drug Code numbers listed below (National Drug Codes can be used to search and identify products online through the FDA). The tablets are either embossed with 101 or 102 on one side and are plain on the other.

Metformin Hydrochloride Extended-Release Tablets, USP 500mg:

90 counts: 49483-623-09

100 counts: 49483-623-01

500 counts: 49483-623-50

1000 counts: 49483-623-10

Metformin Hydrochloride Extended-Release Tablets, USP 750mg:

100 counts: 49483-624-01

Oregon Coronavirus Cases

Data is updated nightly.

Confirmed Cases: 42436

Reported Deaths: 655
CountyConfirmedDeaths
Multnomah9228160
Marion5858108
Washington579076
Umatilla335444
Clackamas313965
Lane239227
Malheur191738
Jackson16846
Deschutes113213
Yamhill99415
Linn81015
Polk65415
Jefferson6049
Morrow5456
Lincoln51713
Union4672
Benton4426
Klamath4113
Douglas3506
Wasco34715
Hood River2771
Josephine2673
Columbia2661
Coos2460
Clatsop2430
Baker1203
Crook1092
Tillamook700
Curry571
Wallowa442
Lake370
Harney230
Sherman190
Gilliam110
Grant110
Wheeler10
Unassigned00

California Coronavirus Cases

Data is updated nightly.

Confirmed Cases: 910438

Reported Deaths: 17386
CountyConfirmedDeaths
Los Angeles3006147000
Riverside667321295
San Bernardino627741072
Orange587251447
San Diego54941870
Kern33881416
Fresno30858436
Sacramento25445484
Santa Clara24313388
Alameda23391461
San Joaquin21630489
Contra Costa18694242
Stanislaus17686397
Tulare17495286
Ventura14300164
Imperial12882336
San Francisco12152140
Monterey1139991
San Mateo11149159
Santa Barbara9814120
Merced9465155
Sonoma9402136
Kings824683
Solano738476
Marin7089128
Madera502074
Placer417857
San Luis Obispo414132
Yolo320759
Butte308752
Santa Cruz280225
Napa196215
Shasta188930
Sutter183712
San Benito144215
El Dorado13284
Yuba129310
Mendocino112921
Tehama8808
Lassen7661
Lake69515
Glenn6573
Nevada6168
Humboldt56710
Colusa5506
Calaveras34218
Amador33016
Tuolumne2714
Inyo22715
Siskiyou1930
Mono1802
Del Norte1781
Mariposa782
Plumas680
Modoc290
Trinity260
Sierra60
Alpine30
Unassigned00
Medford
Clear
36° wxIcon
Hi: 74° Lo: 36°
Feels Like: 36°
Brookings
Clear
58° wxIcon
Hi: 75° Lo: 54°
Feels Like: 58°
Crater Lake
Clear
23° wxIcon
Hi: 65° Lo: 30°
Feels Like: 23°
Grants Pass
Clear
32° wxIcon
Hi: 72° Lo: 33°
Feels Like: 32°
Klamath Falls
Clear
23° wxIcon
Hi: 65° Lo: 24°
Feels Like: 23°
Critical fire danger continues
KDRV Radar
KDRV Fire Danger
KDRV Weather Cam

Community Events