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Expect more cases of strange coronavirus syndrome in kids, doctors warn

The CDC is warning doctors to look out a mysterious illness in children that could be linked to the coronavirus. CNN's Brianna Keilar speaks to a doctor about the symptoms and how to spot any red flags.

Posted: May 14, 2020 3:45 AM
Updated: May 14, 2020 10:00 AM


Parents, hospitals and clinics should expect to see more cases of a mystifying condition that seems to be affecting children after a bout with Covid-19, doctors said Wednesday.

The condition, called multisystem inflammatory syndrome in children, appears to be a post-viral syndrome, said Dr. Jeffrey Burns, a critical care specialist at Boston Children's Hospital who has been coordinating a global group of doctors who compare notes on the condition.

Doctors are investigating cases in at least 150 children, most of them in New York. But a CNN survey finds hospitals and clinics in at least 18 states and Washington, DC are checking into suspected cases.

'This multisystem inflammatory syndrome is not directly caused by the virus,' Burns told CNN. 'The leading hypothesis is that it is due to the immune response of the patient.'

Symptoms include persistent fever, inflammation and poor function in organs such as the kidneys or heart. Children may also show evidence of blood vessel inflammation, such as red eyes, a bright red tongue and cracked lips, said Dr. Moshe Arditi, a pediatric infectious diseases expert at Cedars-Sinai Medical Center in Los Angeles.

British doctors first sounded the alert about the syndrome last month. The Royal College of Paediatrics said Thursday that between 75 and 100 children in Britain had been affected. Italian doctors have also reported the syndrome.

Dr. Ngozi Ezike, director of the Illinois Department of Public Health, said it's a complicated disorder.

'It's a spectrum of disorders, and so in some cases you'll have the individual have coronary artery involvement. Sometimes they don't,' Ezike told a news conference.

A delayed response to infection

Not all of the affected children have tested positive for the coronavirus, but reports from Europe and from several cities in the United States show a link.

'There seems to be delayed responses to Covid infections in these kids,' Arditi said.

Burns believes more cases will turn up as Covid-19 affects more people. It's a rare condition, but rare consequences of viral infections are seen more often when millions of people are infected.

'We can expect that each of the epicenters will see clusters of these emerging roughly four to six weeks later,' Burns told CNN.

'It makes sense that it emerged in New York first because New York had the largest and most severe outbreak (of Covid-19), followed by New Jersey and, unfortunately, Boston.'

Most children are not seriously affected by the syndrome, Burns said. Most don't even need treatment in the intensive care unit, he said, although a very few have died. 'We do have proven treatments that we can use and are using,' he said. They include blood thinners and immune modulators.

The Centers for Disease Control and Prevention is preparing a Health Alert Network notification to send to doctors across the country, a CDC spokesman said. Burns said the World Health Organization is also working to define the syndrome and alert doctors so they will know what to look for and how to treat it.

'This new entity has some similarities to Kawasaki disease,' Arditi told CNN. 'But there are a lot more features that are consistent with toxic shock syndrome, such as multi-organ system involvement and severe abdominal involvement with diarrhea,' he added.

It will be important to study, because the response could help explain why children are so much less likely to be severely affected by Covid-19 than adults are, said Burns.

'Understanding the child's immune response could be a key to vaccine development and could also be a key to therapy for adults to understand why children are able to fight (Covid-19) off so well,' Burns said.

Doctors find suspected cases in 17 states

CNN has contacted departments of health, hospitals and state officials around the country to get a sense of how many children are affected, and where.

Some state health departments told CNN that they are waiting for the CDC alert. 'We are working with the CDC on a case definition and are looking into possible cases, but won't have more until the CDC finalizes its definition,' a spokesman for the Minnesota Department of Health said.

'We don't believe this syndrome is very common, but several cases have been reported elsewhere in association with Covid-19,' said Dr. Paul Cieslak, medical director for infectious diseases and immunizations at the Oregon Health Authority Public Health Division. 'This syndrome appears to be an uncommon but serious complication of Covid-19 in children.'

Paul Mounds, chief of staff for the Connecticut governor's office, said the syndrome would be trackable illness in the state. The Department of Public Health 'sent this out to all the Connecticut pediatric health systems to make sure that they are reporting if these cases are occurring in their facilities, so we can be able to track it and handle it accordingly,' Mounds said Wednesday.

States reporting cases include:

  • California
  • Delaware
  • Illinois
  • Kentucky
  • Louisiana
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • New Jersey
  • New York
  • Ohio
  • Oregon
  • Pennsylvania
  • Tennessee
  • Utah
  • Washington

Oregon Coronavirus Cases

Data is updated nightly.

Cases: 132412

Reported Deaths: 1799
CountyCasesDeaths
Multnomah28237458
Washington18512171
Marion16085238
Clackamas11577138
Lane8219108
Jackson686284
Umatilla670968
Deschutes490736
Yamhill316245
Malheur312452
Linn310246
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Union110416
Wasco106323
Columbia103318
Lincoln98517
Hood River94821
Coos93315
Morrow92710
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Crook60410
Baker5665
Tillamook3622
Curry3185
Lake2295
Grant2131
Harney1734
Wallowa963
Gilliam481
Sherman470
Wheeler201
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California Coronavirus Cases

Data is updated nightly.

Cases: 2955323

Reported Deaths: 33342
CountyCasesDeaths
Los Angeles100392313741
San Bernardino2482851560
Riverside2352352517
San Diego2098972065
Orange2093652320
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San Joaquin56484748
Contra Costa50627430
Stanislaus41925739
Tulare40176501
Monterey34959249
San Mateo31291294
San Francisco28574254
Imperial24944463
Solano24654105
Santa Barbara23538228
Merced23492296
Sonoma23204234
Kings18661110
Placer16761173
San Luis Obispo15129128
Madera12883130
Santa Cruz11776113
Marin11345153
Yolo10240131
Shasta9594117
Butte9233121
El Dorado751544
Sutter748477
Napa723139
Lassen509413
San Benito485043
Yuba481827
Tehama397142
Tuolumne330438
Nevada309973
Mendocino307631
Amador295329
Lake243428
Humboldt226324
Glenn182419
Colusa16919
Calaveras153823
Siskiyou140813
Mono10834
Inyo92429
Del Norte8472
Plumas5735
Modoc3783
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